Real-World Evidence for Sleep Surgery (RWE4S): An Update

Tuesday, October 3, 2023

1:00 PM - 2:00 PM East Coast USA Time

Location: 103A

Moderator(s)

Robson Capasso, MD

Professor, Associate Dean
Stanford University
Stanford, CA, United States

Panelist(s)

Robson Capasso, MD

Professor, Associate Dean
Stanford University
Stanford, CA, United States
Mohamed A. Abdelwahab, MD

Assistant Professor
MUSC
Charleston, SC, United States
Badr Ibrahim, MD

Dr.
University of Montreal, Department of Otolaryngology- Head and Neck Surgery
Montreal, QC, Canada
Thomaz Fleury Curado, MD PhD

Assistant Professor
UH Hospitals Cleveland Medical Center Case Western Reserve University
Cleveland, OH, United States

Disclosure(s):

Robson Capasso, MD: No relevant relationships to disclose.

Mohamed Abdelwahab, MD: No relevant relationships to disclose.

PROGRAM DESCRIPTION: One of the main challenges to define the best OSA treatment path hinges on the accurate definition of “successful result”, as some of the commonly used sleep study metrics have little to no correlation with clinically meaningful outcomes and offer limited perspective on the strategy procedure for each individual. In addition, decisions around treatment selection and in the case of surgery, perioperative routines are based on less than-ideal evidence to support or refute its usefulness. To target this issue, our team gathered multidisciplinary talent with medical, business, computer science, and statistics expertise aiming to collect, refine and analyze large volumes of data presented by claims databases, electronic medical records (EMRs) to produce Real World Evidence, and at the session, we will review published data that will assist in defining clinically relevant deliverables and peri-operative efficient routines.

OUTCOME OBJECTIVE 1: There is a large body of evidence on the impact of surgical interventions for OSA on surrogate endpoints such as the AHI, however, the impact of therapeutic interventions on health-related outcomes is less explored. We will discuss the current evidence on clinically relevant endpoints.

OUTCOME OBJECTIVE 2: Discuss the evidence for peri-operative management of pain and complications and the need for adequate opioid and antibiotic utilization, as for those who are opioid naïve, perioperative opioid prescriptions can be a significant risk factor for prolonged, and inappropriate opioid use.

OUTCOME OBJECTIVE 3: Discuss if treating obstructive sleep apnea with surgery can lessen overall healthcare utilization compared to no treatment and/or CPAP

BACKGROUND STATEMENT: The OSA impact on society is striking. Understanding correctly the magnitude of this problem, and the clinically relevant and econometric goals of OSA treatment well beyond surrogate points as decreased AHI, while minimizing operative risks is crucial to our specialty and patients.