(122) cVEMP Results Differ in VBI with or Without CNS Symptoms

Monday, October 2, 2023

2:45 PM – 3:45 PM East Coast USA Time

Presenting Author(s)

Takaki Inui, MD

Assistant Professor
Osaka Medical and Pharmaceutical University
Takatsuki, Osaka, Japan

Co-Author(s)

SH

Shin-ichi Haginomori, MD

Professor
Osaka Medical and Pharmaceutical University, JPN
TK

Tatsuro Kuriyama, MD

Osaka Medical and Pharmaceutical University, JPN
YI

Yuko Inaka, MD

Osaka Medical and Pharmaceutical University, JPN
KM

Kou Moriyama, MD

Osaka Medical and Pharmaceutical University, JPN
YA

Yusuke Ayani, MD

Osaka Medical and Pharmaceutical University, JPN
RK

Ryo Kawata, MD

Professor
Osaka Medical and Pharmaceutical University, JPN

Disclosure(s):

Takaki Inui, MD: No relevant relationships to disclose.

Introduction: The condition of vestibular functions and blood flow in the vertebral artery (VA) in vertebrobasilar insufficiency (VBI) is not well established. This study was performed to clarify the pathophysiology of VBI, especially the difference between the conditions with or without central nervous system symptoms.

Methods: The medical records of patients were retrospectively reviewed. Ten VBI patients with central nervous system symptoms (VBI/w) and 12 VBI patients without central nervous system symptoms (VBI/o) underwent duplex color-coded ultrasonographic evaluation of VAs, and the vestibular functions evaluated with caloric test, and cervical vestibular-evoked myogenic potential (cVEMP) testing were compared.

Results: The mean flow (MV) ratio (peak MV of contralateral VA divided by target VA) was significantly higher in VBI/w than in VBI/o. There was no difference in the occurrence of canal paresis on caloric test between VBI/w and VBI/o. Abnormal asymmetry ratios (ARs) of cVEMP were observed only in VBI/o cases (6 of 12 cases), revealing a statistically significant difference in the number of cases between VBI/w and VBI/o.

Conclusions: Measuring VA conditions using duplex color-coded ultrasonography and cVEMP may help evaluate VBI. Different results of MV ratio and cVEMP between VBI cases with or without central nervous system symptoms may indicate the differences in pathophysiology between VBI/w and VBI/o.