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Head and Neck Surgery

(287) Is Chronic Liver Disease a Factor in Glossectomy Outcomes?

Monday, October 2, 2023
2:45 PM – 3:45 PM East Coast USA Time
Has Audio

    Presenting Author(s)

  • Owais M. Aftab, BS

    Medical Student
    Department of Otolaryngology – Head and Neck Surgery, Rutgers New Jersey Medical School
    Newark, New Jersey, United States

    • Co-Author(s)

  • AS

    Anthony M. Saad, BA

    Department of Otolaryngology – Head and Neck Surgery, Rutgers New Jersey Medical School, USA

  • Aman M. Patel, BS

    Medical Student
    Department of Otolaryngology – Head and Neck Surgery, Rutgers New Jersey Medical School
    Newark, New Jersey, USA

  • VS

    Vraj P. Shah, BS

    Medical Student
    Department of Otolaryngology - Head and Neck Surgery, Rutgers New Jersey Medical School
    Newark, New Jersey, United States

  • Hannaan S. Choudhry, BA

    Medical Student
    Department of Otolaryngology – Head and Neck Surgery, Rutgers New Jersey Medical School
    Freehold, New Jersey, United States

  • Jean Anderson Eloy, MD, FACS, FACS

    Distinguished Professor and Vice Chair of Otolaryngology - Head and Neck Surgery
    Department of Otolaryngology – Head and Neck Surgery, Rutgers New Jersey Medical School
    West Orange, New Jersey, United States

    • Senior Author(s)

  • Christina H. Fang, MD

    Assistant Professor
    Albert Einstein College of Medicine/Montefiore Medical Center
    Bronx, NY, United States

Disclosure(s):
Owais M. Aftab, BS: No relevant relationships to disclose.
Vraj P. Shah, BS: No relevant relationships to disclose.
Hannaan S. Choudhry, BA: No relevant relationships to disclose.
Jean Anderson Eloy, MD, FACS, FACS: No relevant relationships to disclose.
Christina H. Fang, MD: No relevant relationships to disclose.


Introduction: The MELDNa score is a scoring system for accessing the severity of chronic liver disease. In this study, we evaluated the relationship between chronic liver disease (CLD) and outcomes in patients undergoing glossectomy.

Methods: This retrospective cohort analysis utilized the 2005-2018 National Surgery Quality Improvement Program (NSQIP) database. Current Procedural Terminology (CPT) codes were used to identify cases with a primary procedure of glossectomy, including hemiglossectomy, partial glossectomy, and total glossectomy with or without neck dissection. To identify CLD patients, MELDNa scores were calculated using pre-operative bilirubin, creatinine, international normalized ratio, and serum sodium. CLD patients were identified as having MELDNa greater than 10. Demographics, comorbidities, and complication incidences were compared between CLD and non-CLD patients using chi-square analyses. The independent effect of CLD on adverse outcomes was analyzed using binary logistic regression.

Results: 202 (18.9%) CLD and 867 (81.1%) non-CLD patients undergoing glossectomy were identified from 2005 to 2018. CLD patients more likely had diabetes (11.3% vs. 4.6%; p=0.002), dyspnea (13.9% vs. 5.9%; p< 0.001), hypertension (73.3% vs. 47.9%; p< 0.001), dialysis (2.0% vs. 0.0%; p=0.001) and disseminated cancer (12.4% vs. 6.8%; p=0.013). Additionally, cohorts significantly differed by age (p=0.001) and gender (p < 0.001). After adjusting for patient demographics and comorbidities, logistic regression analyses found that CLD patients had increased odds of postoperative urinary tract infection (OR 9.88; 95% CI 2.24 - 43.67; p=0.003). No significant differences were found in mortality or readmission.

Conclusions: CLD is not associated with an increase in mortality or readmission in patients undergoing glossectomy.