(445) Sialolithiasis: Retrospective Review of Patient Demographics and Predictors of Reoperation

Monday, October 2, 2023

2:45 PM – 3:45 PM East Coast USA Time

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Presenting Author(s)

Shaghauyegh Azar, MD,

Resident Physician
University of California - San Francisco
San Francisco, California, United States

Co-Author(s)

MH

Michelle Hong, Other

University of California, Los Angeles, USA
AM

Avraham Mendelsohn, MD

Associate Professor
University of California - Los Angeles, USA
MH

Michael Holliday, MD

University of California - Los Angeles, USA

Senior Author(s)

Ashley E. Kita, MD

Assistant Professor-in-Residence
University of California, Los Angeles
Los Angeles, California, United States

Disclosure(s):

Shaghauyegh Azar, MD,: No relevant relationships to disclose.

Ashley E. Kita, MD: No relevant relationships to disclose.

Introduction: Sialolithiasis is a common condition of the salivary glands which affects 1.2% of the population. Identifying risk factors for this condition and determining who is most likely to require multiple procedures can help clinicians to better diagnose, manage, and counsel their sialolithiasis patients.

Methods: This is a single institution retrospective review of patients diagnosed with sialolithiasis from 2008 to 2020. Demographic factors, smoking history, comorbid medical conditions, medication history, and clinical evaluation/management were recorded. Analyses with two-tailed correlation coefficients and two-sided chi-square were performed.

Results: A total of 273 cases were identified in 141 men and 133 women. Of these, 82% (220/274) involved the submandibular gland and 18% (48/274) involved the parotid gland. Average age of onset was 51 years. Imaging was obtained in 72% of cases (197/273), and 82% of imaging studies (162/197) confirmed sialolithiasis. Surgical management was pursued in 88% of cases, 54% of which included sialoendoscopy. 3% of patients required multiple procedures. Stone analysis was pursued in 40% of surgical cases; 95% of stones were homogenous, with an average stone size of 9 mm. Stone size was not significantly associated with gland location or duration of symptoms (p>0.05). Smoking, alcohol, and drug use were not significantly related to reoperation (p>0.05). Antiviral use and diuretic use were significantly associated with reoperation (p < 0.05), though the size of these groups was small.

Conclusions: Sialolithiasis is a common condition. In those who underwent a procedure, over half underwent sialoendoscopy. While overall rates of reoperation were low, antiviral and diuretic use were found to increase the need for additional procedures.